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DBCO-NHS ester 2
CAS No. 1384870-47-6
DBCO-NHS ester 2( DBCO-C6-NHS ester )
Catalog No. M11599 CAS No. 1384870-47-6
DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDBCO-NHS ester 2
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NoteResearch use only, not for human use.
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Brief DescriptionDBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry.
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DescriptionDBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry; is useful in strain-promoted copper-free azide-alkyne cycloaddition reactions; used in DNA-assisted protein analysis such as proximity ligation and extention assays, antibody drug conjugates.
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In Vitro——
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In Vivo——
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SynonymsDBCO-C6-NHS ester
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADCs Linker/Click Chemistry
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Research Area——
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Indication——
Chemical Information
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CAS Number1384870-47-6
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Formula Weight430.45
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Molecular FormulaC25H22N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 14.29 mg/mL (33.20 mM)
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SMILESO=C(CCCCC(ON1C(CCC1=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
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Chemical Name2,5-Dioxo-1-pyrrolidinyl 11,12-didehydro-ε-oxodibenz[b,f]azocine-5(6H)-hexanoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tang F, et al. Nat Protoc. 2017 Aug;12(8):1702-1721.
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DBCO-NHS ester
An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
