DBCO-NHS ester 2

CAS No. 1384870-47-6

DBCO-NHS ester 2 ( DBCO-C6-NHS ester )

Catalog No. M11599 CAS No. 1384870-47-6

DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DBCO-NHS ester 2
  • Note
    Research use only, not for human use.
  • Brief Description
    DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry.
  • Description
    DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry; is useful in strain-promoted copper-free azide-alkyne cycloaddition reactions; used in DNA-assisted protein analysis such as proximity ligation and extention assays, antibody drug conjugates.
  • Synonyms
    DBCO-C6-NHS ester
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    ADCs Linker/Click Chemistry
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1384870-47-6
  • Formula Weight
    430.45
  • Molecular Formula
    C25H22N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(CCCCC(ON1C(CCC1=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
  • Chemical Name
    2,5-Dioxo-1-pyrrolidinyl 11,12-didehydro-ε-oxodibenz[b,f]azocine-5(6H)-hexanoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tang F, et al. Nat Protoc. 2017 Aug;12(8):1702-1721.
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